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Zinc Helps To Make A Good Egg And Healthy Embryo

Scientists as well as fertility doctors have long tried to figure out what makes a good egg that will produce a healthy embryo. It’s a particularly critical question for fertility doctors deciding which eggs isolated from a woman will produce the best embryos and, ultimately, babies.

New research reveals healthy eggs need a tremendous amount of zinc to reach maturity and be ready for fertilization – a finding that may ultimately help physicians assess the best eggs for fertility treatment, according to a study from Northwestern University.

“Understanding zinc’s role may eventually help us measure the quality of an egg and lead to advances in fertility treatment,” said Alison Kim, a postdoctoral fellow in obstetrics and gynecology at Northwestern University Feinberg School of Medicine. “Currently we can’t predict which eggs isolated from a woman produce the best embryos and will result in a baby. Not all eggs are capable of becoming healthy embryos.”

There’s no link yet to zinc content in the egg and the nutritional status of women, but Kim plans to research that area.

Kim is the lead author of a paper that will be published in the September issue of the journal Nature Chemical Biology. The article will be featured on the cover. Co-senior authors are Tom O’Halloran, director of the Chemistry of Life Processes Institute at Northwestern and associate director of basic sciences at the Robert H. Lurie Comprehensive Cancer Center of Northwestern University, and Teresa Woodruff, the Thomas J. Watkins Professor of Obstetrics and Gynecology and executive director of the Institute for Women’s Health Research at Feinberg. Woodruff also is a member of the Lurie Cancer Center.

Northwestern scientists, working with mice, discovered the egg becomes ravenous for zinc and acquires a 50 percent increase in the metal in order to reach full maturity before becoming fertilized. The flood of zinc appears to flip a switch so the egg can progress through the final stages of meiosis. Meiosis is when the egg sheds all but one copy of its maternal chromosomes before it can be fertilized by a sperm and become an embryo.

“Zinc helps the egg exit from a holding pattern to its final critical stage of development,” said O’Halloran, the Charles E. and Emma H. Morrison Professor of Chemistry in the Weinberg College of Arts and Sciences at Northwestern. “It’s on the knife’s edge of becoming a new life form or becoming a cell that dies. It only has 24 hours. Zinc seems to be a key switch that helps control whether the egg moves forward in its development stage. ”

Kim found there were approximately 60 billion zinc atoms in a mouse egg just before the egg was ready to be fertilized. She measured the zinc content of the eggs using a technique called synchrotron-based X-ray fluorescence microscopy through collaboration with the Advanced Photon Source at Argonne National Laboratory. This method allowed detection of multiple metals in single eggs using the characteristic X-ray signature of each element.

Zinc levels were significantly higher in eggs than other important metals such as iron and copper. Zinc was the only metal to change significantly in concentration during the maturation process.

Northwestern scientists also used small molecules to block the accumulation of zinc by the maturing egg. They found an insufficient accumulation of zinc caused all the eggs to pause prematurely at the beginning stage of meiosis. The progression of meiosis was restored by returning zinc to the eggs.

Research on the role of zinc was funded by a W.M. Keck Foundation Medical Research Award, the Center for Reproductive Science through the NIH/National Institute of Child Health and Human Development and the Chemistry of Life Processes Institute at Northwestern University through NIH/National Institute of General Medicine. Use of the Advanced Photon Source at Argonne National Laboratory was supported by the Office of Basic Energy Sciences in the Office of Science of the U.S. Department of Energy.

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Passive compilation

Originally, your brain did not have a concept of good or evil. It was pure innocence personified. Whether you wanted it to or not, this society has filled your brain with information that has defined good and evil, delineated between mine and yours, and created other various value judgments that you make every day. The “I” has become a passive compilation of various information that has been fed you when someone asks, “Who are you?” you tell him your name. When someone else asks, “Who are you?” you tell him your occupation. However, your name and your job are not who you truly are.

Ilchi Lee is the author of 26 books including Healing Society he says religion is another piece of information that has been embedded into your brain. Even life and death are just pieces of information that are occupying your brain. When you erase all the information in your brain, you will be left with just the brain itself, and the source of all life. This doesn’t mean that you will become amnesiac. It means that you will be free of all the emotional baggage that comes with the information you have received and will be able to look at it with a truly fresh and objective perspective, ultimately using this information to make positive changes to your life.

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Develop the energy system

Certainly, there have been many practices throughout history that recognized and sought to develop the energy system of the body. In fact, this is the ultimate goal of many martial arts in Asia: to strengthen the body by utilizing the energy flow that animates the physical body. But we have never before used this energy flow in a systematic way to strengthen our spiritual body. We have never purposefully utilized the energy flow that circulates through our bodies to connect our life force to the Cosmic Force and thereby to everything and everyone—realizing the Oneness not on an intellectual or even philosophical plane, but reeling it with every single fiber of our being, imprinted onto every one of our cells through a profound experience.

Imagine lecturing about water to someone who has never seen, felt, or touched it. Imagine describing the feel, taste, texture, density, and everything else that makes up water in order to make this person understand what water is. Now imagine lifting up this person and throwing him into a pool. Which do you think will be more effective in teaching him what water truly is? Personal experience, personal connection to the Oneness, is the key to enlightenment.

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Cosmic Energy

How do we do that? How do we make people realize that Cosmic Mind is our minds and that Cosmic Energy is our energy and that we are all part of this majestic Cosmic Order? How do we make people realize that we are one in Yuln’yo, much the same way we realize that we need to breathe to live? How do we make this knowledge instinctive? Or more accurately, how do we cause this already instinctive knowledge to surface to our immediate awareness and be acted upon consciously? We can’t teach through words, for this is not something that can be understood intellectually. History has proven that the various political and economic systems have proven ineffective in teaching people this Truth, if even attempted. Even religions have failed, maybe not with certain select individuals, but certainly on a massive scale. So, how do we awaken the spirituality that we know lies within us? How do we get in touch with the divinity, the same, all-encompassing divinity, that we all share? How?

Energy is the answer or Ki, in Eastern traditions. This is the key element that has been lacking in the stye eye infection traditions of the world. Energy is what connects the body, mind, and spirit. It is the common bond that holds the three together, while not being limited to any single form. And energy can be the path through which ordinary people can feel the connection to Chunji Kiun, or the Cosmic Energy. The source whence we all came. Yulriyo.
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